Diabetica Frio bag remains cool for several days through a process of evaporation thus must not be placed into air-tight containers. External mesh pockets are the ideal location to carry. It can be reactivated. Keeps insulin cool for >45 hours.

The FRIO Insulin Cooling Case is a reusable evaporative cooler whose cooling properties do not come from an icepack - or anything that needs refrigeration. Its cooling properties come from the evaporation of water. When activated, it keeps its low temperature for a minimum of two days, even in temperatures of 100 degrees Fahrenheit.

With the FRIO, the person dependent on medication that must remain cool is not dependent on ice packs in any way or at any time.