Depression and insomnia are two of the most prevalent concerns for which patients will seek medical treatment. 5-Hydroxytryptophan (5-HTP) is derived from the seed of Griffonia simplicifolia and is a precursor needed for the synthesis of the neurotransmitter serotonin as well as for the neurohormone melatonin. Serotonin is synthesized in the intestinal tract by the enteric cells as well as in the central nervous system. Orally administered serotonin is not able to cross the blood-brain barrier, and therefore cannot enter the CNS. 5-HTP, however, is able to cross the blood-brain barrier, where it can then be utilized as a precursor to generate serotonin. Serotonin plays a role in regulating mood, sleep, appetite, sexuality, body temperature, and aggression.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.