Highlights

• Preservative-free
• Contains glycerin (0.5%) and sodium hyaluronate
• Two 10mL (0.33 fl oz) PF multi-dose bottles

Rebecca's description

March 2025

I've always liked the BioTrue Hydration Boost brand products and I'm glad we were finally able to stock them. 

BioTrue Hydration Boost is sold in both unit dose vials and MDPF bottles. This 2-pack is a decently economical way to get a lot of HA drops.

This is a very comfortable drop that lasts a decent time. I've always been a fan of sodium hyaluronate eye drops (though of course each one is different). I would never hesitate to recommend this as a starter drop or as a daytime drop. I think of Oasis Tears Plus and a couple of the Optase brand drops as the best choice for those with the most severe symptoms, then Biotrue Hydration Boost and Systane Hydration as kind of the "medium strength" workhorse eye drops.

With all eye drops containing sodium hyaluronate , there is a complication that makes it difficult and frustrating to compare any two eye drops on their merits. The complication is that the hyaluronate, which is a lubricant and may be listed as hyaluranon, sodium hyaluronate or hyaluronic acid, is always listed in the "inactive" ingredients list. This in turn means that we are not told the concentration.

As a result, we can't compare any eye drops based on their concentration of sodium hyaluronate, which is really annoying. Why is this the case? It's a complicated regulatory anomaly. SH is actually not supposed to be used an active ingredient at all. Before you start blaming the FDA, believe it or not, this one is 100% the fault of industry. It's a long story and we hope it won't be too much longer before this problem is fixed - considering there are now more than 22 eye drop products on the market that contain sodium hyaluronate!

Manufacturer's description

Biotrue Hydration Boost Eye Drops are preservative free drops that provide instant moisture to eyes that are dry and irritated from screen and environmental stressors.

Drug Facts

Active ingredients

Glycerin (0.5%)

Uses

For the temporary relief of burning and irritation due to dryness of the eye. For the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun.  For use as a protectant against further irritation or to relieve dryness of the eye. 

Warnings

For external use only

Do not use

• if this product changes color or becomes cloudy
• if tamper evident ring is broken or missing

When using this product

• do not touch tip of container to any surface to avoid contamination
• replace cap after each use

Stop use and ask a doctor if you experience any of the following:

• eye pain
• changes in vision
• continued redness or irritation of the eye
• condition worsens or persists for more than 72 hours

 Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

• remove tamper evident ring, then remove cap
• tip bottle at a downward angle or upside down (to deliver drop to eye)
• squeeze bottle to instill 1 or 2 drops in the affected eye(s) as needed
• replace cap after use

Other information

store at room temperature

Inactive ingredients

boric acid, erythritol, potassium chloride, purified water, sodium borate, sodium hyaluronate