A man with a genius IQ follows in his father’s footsteps in more ways than one. Park Hoon (Lee Jong Suk) is raised in North Korea to become a doctor by his doctor father, who had defected to South Korea years ago and met his South Korean mother before being captured and returned to North Korea. After Park Hoon becomes an accomplished chest surgeon, he too defects to South Korea and goes to work in the prestigious Dongwoo University Hospital. As he tries to adjust to his strange new life in South Korea, Park Hoon does his best to work alongside Han Jae Joon (Park Hae Jin), a Harvard graduate who first discovers Park Hoon’s talent, while catching the eye of Oh Soo Hyun (Kang So Ra), Jae Joon’s fiance and the daughter of the hospital chairman. Anesthesiologist Song Jae Hee bears a strong resemblance to Han Seung Hee (both played by Jin Se Yun), Park Hoon’s girlfriend back in the North whom he wants desperately to come join him. Can the genius doctor do what it takes to make a new life for himself and his love in the South?

擁有天才智商的人跟隨他的父親在很多方面的腳步。公園勳（李鍾碩）在朝鮮提出由他的醫生的父親，誰前叛逃到韓國年被捕獲並返回到朝鮮以前見過他的韓國母親成為一名醫生。經過公園勳成為一個多才多藝的胸部外科醫生，他太缺陷韓國，轉移至著名的東宇大學醫院工作。當他試圖調整在韓國的他奇怪的新生活，樸勳做他最好的旁邊韓在俊（樸海鎮），畢業於哈佛大學的工作誰首先發現公園勳的人才，而醒目哦銖賢的眼睛（姜素拉），宰俊的未婚夫和醫院董事長的女兒。麻醉醫師宋在熙具有強的相似韓升熙（均由金色韻飾），在他要拼命為之北園勳的女朋友回過來和他一起。天才醫生能做些什麼才能使新的生活為自己和他在南方的愛情嗎？