New Roots Herbal Joyful contains 11 botanical extracts, amino acids, and bioactive forms of the vitamins pivotal for mood. The therapeutic goal of Joyful is twofold: to elevate mood and to strengthen resistance to triggers that generate stress.

Six of the nutrients in New Roots Herbal Joyful—5-HTP, ʟ‑tryptophan, vitamin D3, methylfolate, methylcobalamin, and vitamin B6—collectively support serotonin production and neurotransmitter metabolism. The additional five constituents in Joyful—ʟ‑theanine, gamma‑aminobutyric acid (GABA), magnolia, phellodendron, and san qi—reduce excitability within the nervous system to endorse a sense of calm.