The purpose of the book is to promote the art of good history taking and clinical examination, and reaching the final diagnosis by obtaining only a few selective investigations or special evaluations. The book highlights the classical and systematic approach towards diagnosis of the disease. Each case study has been carefully designed to simulate the clinical practice scenarios as far as possible in order to evoke the right patient approach and clinical decision making. Unlike the small clinical vignettes described in most other books, detailed explanation of the pathology relevant to the case study in question has been described in all the chapters. One of the key features of this book is its versatility. Not only will the book be useful to the undergraduates who are required to get acquainted with the clinical examination skills but also for the busy postgraduates who are in the rush to go through the clinical scenarios.