This antibody portfolio includes a wide range of tissue- & tumor-specific primary antibodies for basic research, product development and analysis of a variety of biological questions. The monoclonal antibodies are perfectly applicable for all cell or tissue biology studies and for the analysis of predictive markers in research.

Antibody recognizes desmoglein 2 present in low concentrations in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells desmoglein 2 expression is generally very low. Polypeptide reacting: desmoglein 2 (1069aa; calculated mol. wt. 116,760) Reactivity on cultured cell lines: many, including CaCo-2, HaCaT, MCF-7

Immunohistochemistry (IHC) - frozen: 1:100 (5 μg/ml, for better resolution preincubation (directly after fixation) with 0.05-0.2 % Triton X-100 for 5-10 min, depending on tissue type, is recommended (Schäfer S. et al., 1996)) Western Blot (WB): assay dependent