GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively.

Product information

CAS Number: 494191-73-0

Molecular Weight: 342.34

Formula: C17H11FN2O3S

Chemical Name: 4-{[(2E,5Z)-2-[(2-fluorophenyl)imino]-4-hydroxy-2,5-dihydro-1,3-thiazol-5-ylidene]methyl}benzoic acid

Smiles: OC1=N/C(=N\C2=CC=CC=C2F)/S/C/1=C\C1=CC=C(C=C1)C(O)=O

InChiKey: SYCKPHBALHXMIR-ZROIWOOFSA-N

InChi: InChI=1S/C17H11FN2O3S/c18-12-3-1-2-4-13(12)19-17-20-15(21)14(24-17)9-10-5-7-11(8-6-10)16(22)23/h1-9H,(H,22,23)(H,19,20,21)/b14-9-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

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